Impact of a cream containing madecassocide and 5% panthenol in post photodynamic therapy procedure for actinic keratosis: A randomized, controlled trial

Photodynamic therapy (PDT) is a widespread and recognized method for the treatment of skin cancer and precursors to skin cancer (actinic keratoses). After PDT therapy, the skin will be red and swollen and small sores and blisters may form after a few days. Recent research projects have shown that cream containing anti-inflammatory ingredients can reduce skin reactions and shorten recovery time after PDT.

This research project looks at the effect of Cicaplast Baume B5+ cream after PDT therapy of actinic keratoses. 20 patients participate in the project. Each patient will use the cream over 14 days with five follow-up visits. Two symmetrical treatment areas are selected, one of which is treated with Cicaplast Baume B5+ cream after PDT treatment. For the follow-up visits, the participants' skin is examined for local skin reactions by clinical examination using new non-invasive imaging technologies.

The purpose of the research project is to contribute important knowledge about post-treatment following PDT and potentially benefit the many patients who are treated for skin cancer and precursors to skin cancer each year.