Research project (completed)

Determination of DNA repair products in urine after UV irradiation of the skin

The project is a scientific experiment focusing on DNA damage, personal biofeedback and risk perceptions in relation to the development of skin cancer.

The project is a collaboration between the Danish Research Center for Skin Cancer and the Danish Cancer Society, focusing on a scientific experiment based on a new method. We measure compounds related to DNA damage excreted in the urine after UV exposure in a group of Danes who was away on winter sun holiday in the beginning of 2023.

In addition, we conducted qualitative interviews to investigate how our group of travelers reacted to personal biofeedback and whether it changed their perception of risk in relation to development of skin cancer.

Researchers

Pharmacist Jonatan Granborg

Special Consultant Nynne Johanne Sahl Frederiksen

Master Thesis student Ida Schwarz Thorsteinsson

Senior Researcher Brian Køster

Senior Researcher Peter Alshede Philipsen

Engineer Jakob Heydenreich

 

Project supervisors

Professor Hans Christian Wulf

Professor Merete Hædersdal

Project Manager Peter Dalum

Associate Professor Catharina Lerche

Project period

2023

Project collaborators

Danish Research Center for Skin Cancer

Danish Cancer Society

Water Corporation

Financing

Danish Research Center for Skin Cancer

Danish Cancer Society

Selected publications

Lerche CM, Philipsen PA, Hermansson S, Heydenreich J and Wulf HC. Quantification of Urinary Thymine Dimers in Volunteers After Ultraviolet Radiation Using a New UPLC-MS/MS-based Method. Anticancer Res 2022. Oct;42(10):5069-5076.