Line-Field Confocal Optical Coherence Tomography in Dermato-Oncology: Opportunities and Challenges of Optical and Transcriptomic Biomarkers

Skin cancer is the most prevalent form of cancer worldwide. Line-Field Confocal Optical Coherence Tomography (LC-OCT) is a non-invasive optical imaging technique that enables cellular level visualization of the skin and has been employed to characterize skin cancer. Tape stripping is used to measure gene expression.

In this study, we aim to explore two non-invasive methods, LC-OCT and tape stripping, for their capability to assess skin cancer. We will compare the results from these two methods with clinical evaluation to better distinguish different types of skin cancer. Our goal is to improve the outcome of patients with skin cancer by enabling earlier detection and personalized treatment options for those affected by skin cancer.