Beatrice Dyring-Andersen
Department of Dermatology, Zealand University Hospital,
Sygehusvej 10
4000 Roskilde
Denmark
Current research:
My research focuses on mass spectrometry-based proteomics applied to inflammatory and rare skin diseases. Using state-of-the-art instrumentation and spatial proteomics techniques such as laser capture microdissection, we map the proteome of skin conditions including melanoma, Merkel cell carcinoma, extramammary Paget's disease and sebaceous carcinoma. A key aim is to identify novel disease mechanisms, biomarkers, and therapeutic targets to advance precision dermatology. Across projects, we combine well-phenotyped patient cohorts with advanced proteomics workflows to move from molecular discovery toward clinical application. Our team leads the open-access skin.science data platform, which has reached researchers in over 127 countries.
Main interests
1) Translational skin research and global health 2) Mass spectrometry-based proteomics, spatial proteomics and precision dermatology 3) Rare skin cancers (Merkel cell carcinoma, EMPD, melanoma) Inflammatory skin diseases and fungal skin infections and diagnostics
PhD
Innate lymphoid cells and gamma delta T cells in inflammatory skin disease: A study of prevalence and phenotype in psoriasis and contact allergy. Enrolled: December 2011. Defended: November 2014. University of Copenhagen.
Publications
1) Rosager AM, Kabatnik S, Zhang Y, Agerbæk S, Bzorek M, Løvendorf MB, Dyring-Andersen B. Identification of Merkel Cell Polyomavirus Oncoproteins by Mass Spectrometry-Based Proteomics. J Invest Dermatol. 2025 Aug 13:S0022-202X(25)02339-5. PMID: 40816657.
2) Møller LBP, Kromann B, Kabatnik S, Hjortlund JH, Haulrig MB, Sølberg J, Bzorek M, Clark RA, Skov L, Mann M, Løvendorf MB, Dyring-Andersen B. Spatial proteomic profiling reveals increased levels of cholesterol synthesis proteins in psoriasis vulgaris. J Invest Dermatol. 2025 May. PMID: 40412467.
3) Naimy S, Sølberg JBK, Kuczek DE, Løvendorf MB, Bzorek M, Litman T, Mund A, Rahbek Gjerdrum LM, Clark RA, Mann M, Dyring-Andersen B. Comparative quantitative proteomic analysis of melanoma subtypes, nevus-associated melanoma, and corresponding nevi. J Invest Dermatol. 2024;144(7):1608–1621.e4.
4) Pruessmann W, Rytlewski J, Wilmott J, et al., Dyring-Andersen B, et al. Molecular analysis of primary melanoma T cells identifies patients at risk for metastatic recurrence. Nature Cancer. 2020;1(2):197–209.
5) Dyring-Andersen B, Løvendorf MB, Coscia F, Delgado AS, Møller LBP, Niu L, Andersen JL, Clark RA, Skov L, Teunissen MBM, Mann M. Spatially resolved proteomic atlas of human skin and its associated immune system. Nature Communications. 2020;11:5587.
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