Tumor Biomarkers by Mass Spectrometry Imaging: Discovering the Skin Cancer Signature

The project’s aim is to combine MSI diagnostics with real time skin cancer treatment by introducing a new surgical technique called “REIMS”. The REIMS technique performs mass spec-based identification of the aerosolised tissue produced during electrosurgical dissection. While REIMS has yet to be applied to skin cancer, the technique is previously tested on eight different cancer forms with highly promising results.

Before introducing REIMS to skin cancer management, seminal studies are necessary to identify biomarkers that differentiate malignant and normal skin. To achieve that goal, our project bridges clinical experts who have patient access, with scientists who provide theoretical insights and

valuable analytical methods. By creating a dynamic and multidisciplinary front, we intend to provide synergistic impact, translating into improved treatment, reduced tumor recurrence, less patient morbidity and lower socio-economic costs.